HealthMedical Science

Nanoparticles for Fighting Cancer

by Nabila Rab

Nanotechnology is a technology where we operate substances at exceptionally minor masses. We use this technology for changing elements. Nanomaterials are used in customer goods and our modern medical treatments. And there is another use of nanotechnology, which is to battle in contradiction of cancer targets to find the tumor at a prior stage. Nanoparticles intended for adding the cancer cells and mark tumors detectable in scans before the growth of the syndrome. Cancer treatment is too brutal for anyone, and we all know that. Surgery, radiation, and chemotherapy – all of these are traditional cancer treatments, and these treatments harm the cancer cells with also healthy cells. Nausea, vomiting, hair loss, and infections are the side effects of those treatments. But it is so sad for us because there is no promise of a cure. An experiment has shown that nanoparticles can be used to harm and even destroy cancer cells. Ludwig Maximilian University of Munich (LMU) researchers have developed one kind of nanoparticle which could release drugs selectively inside tumors by keeping healthy cells safely locked.

They tested it on cultured cells and in living mice. And they established that some cancer-particular mechanism splits the outer membrane and originates toxic mixtures to escape out. In the intervening time, the mixtures remain locked up in healthy cells and pass into the extracellular matrix to be cleared away. In simple words, a high laser temperature activates the nanoparticles then harms or destroys the cancer cells. 

Nanoparticles Kill Cancer - ASME

Hanna Engelke said that “With only two doses, administered locally, we were able to reduce tumor sizes by 40 and 70 percent, respectively. But clearly, the particles can be highly toxic to cancer cells.” This new type of nanoparticles could discharge their drugs inside cancer cells. Those particles are amorphous, porous, and encapsulated in a lipid layer. These could simply be occupied by cells without activating a resistant reaction. When they are inside, the lipid layer breaks down and discharges the drug, which is the sum of calcium and citrate. We know that these mixtures destroy cells when supplied in a straight line into them. The lipid layer breaks down inside tumors when the particles are similarly taken up from healthy and cancerous cells.

The experiment also indicated no symbols of serious lateral belongings next two months. Researchers said –“This technique  could mostly be suitable for cancers that arise in the pleural hole (the thin, fluid-filled gap that surrounds the lungs), which is a mutual site for lung cancer.”


Nabila Rab

Genetic Engineering & Biotechnology

East West University

Sources:

1.Fighting cancer using nanotechnology – ECHA.

2.Nanomaterials for cancer therapies

3.Treatment of cancer by using Nanoparticles as a Drug Delivery | Insight Medical Publishing

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